Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35261 | 0.65 | — | — | |
| SCHEMBL6364359 | 0.65 | BRD4 (0.37) | BRD4 | |
| SCHEMBL9354170 | 0.58 | — | — | |
| SCHEMBL17004509 | 0.57 | — | — | |
| SCHEMBL762384 | 0.57 | — | — | |
| SCHEMBL3369576 | 0.54 | — | — | |
| SCHEMBL2216732 | 0.53 | KDM4E (0.33) | — | |
| SCHEMBL17803192 | 0.53 | — | — | |
| SCHEMBL4944740 | 0.53 | BRD4 (0.53) | BRD4 | |
| SCHEMBL17146127 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353910-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002040451-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |