Diphenylether

Diphenylether

SCHEMBL7158148

C1COCCO1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.67
TSHR P16473 1/20 0.67
LMNA P02545 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
KMT2A Q03164 1/20 0.52
HTT P42858 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
POLB P06746 1/20 0.48
HSD17B10 Q99714 1/20 0.47
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
MAOB P27338 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL4639231 0.97 LTA4H (0.71) LTA4HTSHRLMNASMN1; SMN2KMT2A
Diphenylether SCHEMBL25438645 0.92 LTA4H (0.63) LTA4HTSHRLMNASMN1; SMN2KMT2A
Diphenylether SCHEMBL3336926 0.90 LTA4H (0.60) LTA4HTSHRLMNASMN1; SMN2KMT2A
Diphenylether SCHEMBL27459589 0.85 LTA4H (0.92) LTA4HTSHRKMT2ANR1H2BAX
Diphenylether SCHEMBL27682484 0.84 LTA4H (0.56) LTA4HTSHRLMNASMN1; SMN2KMT2A
Diphenylether SCHEMBL29263430 0.82 LTA4H (0.86) LTA4HTSHRKMT2ANR1H2BAX
Diphenylether SCHEMBL9061108 0.82 LTA4H (1.00) LTA4HTSHRKMT2ANR1H2BAX
Diphenylether SCHEMBL12286 0.82 LTA4H (1.00) LTA4HTSHRKMT2ANR1H2BAX
Diphenylether SCHEMBL4950525 0.82 LTA4H (1.00) LTA4HTSHRKMT2ANR1H2BAX
Diphenylether SCHEMBL2461810 0.82 LTA4H (1.00) LTA4HTSHRKMT2ANR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1219775-C Halogen contained aromatic compound NIPPON CATALYTIC CHEM IND (JP) 2005-09-21 CN disclosed
US-20030170424-A1 Method for bonding and debonding films using a high-temperature polymer ROBERDS BRIAN (US) 2003-09-11 US disclosed
CN-1385427-A Halogen contained aromatic compound NIPPON CATALYTIC CHEM IND (JP) 2002-12-18 CN disclosed
US-4453946-A Dyeing assistant and use thereof in dyeing synthetic fibre material CIBA-GEIGY CORPORATION (US) 1984-06-12 US disclosed