Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.71 |
| ▸ | CTSS | P25774 | 6/20 | 0.71 |
| ▸ | CTSL | P07711 | 2/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.71 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.62 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376611 | 0.94 | CAPN1 (0.64) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7154598 | 0.92 | CTSK (0.65) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7158540 | 0.92 | CTSK (0.71) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934709 | 0.89 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL11361534 | 0.89 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7402633 | 0.89 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7411658 | 0.89 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7165207 | 0.88 | CTSK (0.70) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL24115146 | 0.87 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL20669315 | 0.87 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635621-B1 | Alpha amino acid amide derivatives; reducing cathepsins B, L, S and/or K activity | NAEJA PHARMACEUTICAL INC. (CA) | 2003-10-21 | — | — | US | disclosed |