SCHEMBL7158293

SCHEMBL7158293

CNCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)CCNC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20463099 0.94
SCHEMBL5145675 0.90 LMNA (0.31)
SCHEMBL5145562 0.90 LMNA (0.31)
SCHEMBL5146898 0.90 LMNA (0.31)
SCHEMBL5146893 0.86
SCHEMBL23168938 0.85
SCHEMBL18284561 0.82 PRMT3 (0.35)
SCHEMBL20714611 0.78
SCHEMBL6849092 0.76 EPHX1 (0.31)
SCHEMBL5145381 0.76 EPHX1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6552161-B1 Fluorinated diamine; it's polyamic acid and polyimide with at least one tetracarboxylic dianhydride ELSICON, INC. 2003-04-22 US disclosed
US-6451960-B1 POLYAMIC ACIDS PREPARED FROM POLARIZABLE FLUORINATED AMINES AND AT LEAST ONE TETRACARBOXYLIC DIANHYDRIDE AND THE CORRESPONDING POLYIMIDES DERIVED THEREFROM ELSICON, INC. 2002-09-17 US disclosed
US-6084057-A POLYAMIC ACID WHERE THE AMINE COMPONENT IS A POLARIZABLE DIAMINE HAVING A FLUOROCARBON MOIETY AND POLAR GROUP COMPRISING A PI ELECTRON SYSTEM CONTAINING AT LEAST ONE HETEROATOM; POLYIMIDE THEREFROM ELSICON, INC. (US) 2000-07-04 US disclosed
WO-1998053361-A2 POLARIZABLE AMINES AND POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS ALLIANT TECHSYSTEMS INC. (US) 1998-11-26 WO disclosed