Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.46 |
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7153982 | 0.93 | F10 (0.47) | BRD4F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7153785 | 0.90 | F2 (0.46) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7152729 | 0.88 | ALDH1A1 (0.54) | PRSS1PRSS2PRSS3F2MRGPRX1 | |
| Trifluoroacetic Acid SCHEMBL7155254 | 0.88 | POLB (0.48) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7157225 | 0.86 | NR1H4 (0.51) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7153335 | 0.85 | BRD4 (0.51) | BRD4F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7152732 | 0.83 | F10 (0.47) | BRD4F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7154028 | 0.83 | F2 (0.43) | F10PRSS1PRSS2PRSS3F2 | |
| Trifluoroacetic Acid SCHEMBL7154799 | 0.83 | F10 (0.49) | BRD4F10F2MRGPRX1F3 | |
| Trifluoroacetic Acid SCHEMBL7153799 | 0.82 | ALDH1A1 (0.51) | F10PRSS1PRSS2PRSS3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |