Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | FOS | P01100 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885070 | 0.87 | TSHR (0.57) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL16991795 | 0.85 | TSHR (0.63) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL178482 | 0.84 | TSHR (0.62) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2728020 | 0.83 | TSHR (0.76) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL28410494 | 0.82 | TSHR (0.59) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL19326715 | 0.82 | TSHR (0.59) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL20467155 | 0.81 | HTR1A (0.58) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL16564149 | 0.81 | NFKB1 (0.71) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL20821290 | 0.81 | TSHR (0.58) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL24182045 | 0.80 | TSHR (0.57) | TSHRCYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030188344-A1 | Compositions and methods for agrobacterium transformation of plants | PENNSYLVANIA UNIVERSITY OF | 2003-10-02 | — | — | US | disclosed |