Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.68 |
| ▸ | PPARA | Q07869 | 15/20 | 0.68 |
| ▸ | PPARD | Q03181 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158393 | 1.00 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL12616950 | 1.00 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL6967147 | 0.91 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6967143 | 0.91 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL8846002 | 0.90 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL8845995 | 0.90 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL12616962 | 0.89 | PPARA (0.66) | PPARGPPARAPPARD | |
| SCHEMBL8340707 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL8340720 | 0.88 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL7158278 | 0.88 | PPARG (0.62) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552058-B1 | For therapy of diabetes or hyperlipidemia | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6147099-A | USEFUL AS ANTI-DIABETICS OR HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5972970-A | COMPOUNDS SUCH AS 5-(3-(2-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL) ETHOXYL-5-PYRIDYL)PROPYL)-2,4-OXAZOLIDINEDIONE; ADMINISTERING TO TREAT A MAMMAL SUFFERING FROM DIABETES OR HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0612743-B1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-5665748-A | ANTIDIABETIC, HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0612743-A1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |