SCHEMBL8846002

SCHEMBL8846002

Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.72
PPARA Q07869 17/20 0.72
PPARD Q03181 8/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845995 1.00 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL7161684 0.93 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL7161681 0.93 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL7161688 0.93 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL8340707 0.91 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL8340720 0.91 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL7166869 0.91 PPARA (0.60) PPARGPPARAPPARD
SCHEMBL7166876 0.91 PPARA (0.60) PPARGPPARAPPARD
SCHEMBL7158396 0.90 PPARG (0.68) PPARGPPARAPPARD
SCHEMBL12616950 0.90 PPARG (0.68) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5591862-A ANTILIPEMICS, TREATING DIABETES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-07 US disclosed