Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.69 |
| ▸ | PPARA | Q07869 | 16/20 | 0.69 |
| ▸ | PPARD | Q03181 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340707 | 1.00 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL8846002 | 0.91 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL8845995 | 0.91 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL7162169 | 0.90 | FFAR1 (0.64) | PPARGPPARA | |
| SCHEMBL7162171 | 0.90 | FFAR1 (0.64) | PPARGPPARA | |
| SCHEMBL7158393 | 0.88 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL12616950 | 0.88 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL7158396 | 0.88 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL6967143 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6967147 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |