Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364554 | 0.90 | F2 (0.57) | F2PRSS1 | |
| SCHEMBL7159962 | 0.87 | F2 (0.70) | F2PRSS1 | |
| SCHEMBL5474623 | 0.87 | F2 (0.52) | F2PRSS1 | |
| SCHEMBL5474694 | 0.86 | F2 (0.64) | F2PRSS1 | |
| SCHEMBL5479394 | 0.85 | F2 (0.50) | F2PRSS1 | |
| SCHEMBL5475081 | 0.82 | KDM4E (0.47) | F2PRSS1 | |
| SCHEMBL6957416 | 0.79 | F2 (0.70) | F2PRSS1 | |
| SCHEMBL3238207 | 0.79 | F2 (0.64) | F2PRSS1 | |
| SCHEMBL7151089 | 0.77 | F2 (0.71) | F2PRSS1 | |
| SCHEMBL7159467 | 0.77 | F2 (0.73) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534510-B2 | Anticoagulants | MERCK & CO., INC. | 2003-03-18 | — | — | US | disclosed |
| US-20020006923-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006923-A1 | Thrombin inhibitors | F2, F11, F12 | F2 1/4885PRSS1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.