Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15287706 | 0.75 | CA2 (0.46) | CA2FAAHTSHR | |
| SCHEMBL6050006 | 0.71 | CA2 (0.50) | CA2FAAHTSHR | |
| SCHEMBL3260166 | 0.71 | CA2 (0.50) | CA2FAAHTSHR | |
| SCHEMBL28140285 | 0.69 | CA2 (0.53) | CA2FAAHTSHR | |
| SCHEMBL7684838 | 0.69 | TP53 (0.35) | TSHR | |
| SCHEMBL15287703 | 0.68 | CA2 (0.42) | CA2FAAH | |
| SCHEMBL5879379 | 0.67 | TSHR (0.38) | FAAHTSHR | |
| SCHEMBL3051208 | 0.66 | CA2 (0.53) | CA2FAAH | |
| SCHEMBL6049941 | 0.66 | CA2 (0.39) | CA2FAAHTSHR | |
| SCHEMBL28114649 | 0.66 | TSHR (0.41) | FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029241-A1 | CHK1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |