Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7158701 | 0.93 | F2 (0.53) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7153324 | 0.92 | F2 (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7157233 | 0.91 | PRSS1 (0.55) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7148990 | 0.89 | PLA2G7 (0.46) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.88 | F2 (0.48) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7155325 | 0.87 | F2 (0.47) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7151221 | 0.86 | ST14 (0.62) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7153927 | 0.85 | F2 (0.49) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7153672 | 0.84 | F2 (0.47) | F2ST14PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7150780 | 0.84 | PRSS1 (0.55) | F2ST14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |