SCHEMBL715894

SCHEMBL715894

CC(=O)NN1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6123494 0.97 HTT (0.45)
SCHEMBL637498 0.97 HTT (0.45)
SCHEMBL19052251 0.94
SCHEMBL29107984 0.92 CA2 (0.41)
SCHEMBL9613513 0.88
SCHEMBL8033657 0.85 HTT (0.50)
Trifluoroacetic Acid SCHEMBL6218638 0.85 HTT (0.38)
SCHEMBL14500231 0.82 CA12 (0.53)
SCHEMBL4685447 0.80 HTT (0.31)
SCHEMBL10155509 0.79 CA12 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124489-A1 SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2024-04-18 US claimed
CN-115785070-B Pyrrolidinyl acetamide derivative, preparation method and application thereof 桂林医学院附属医院 2023-06-09 CN claimed
CN-114761404-A Substituted bicyclic heteroaryl compounds 百时美施贵宝公司 2022-07-15 CN claimed
US-20210121397-A1 BIODEGRADABLE INTRAVITREAL TYROSINE KINASE IMPLANTS ALLERGAN INC (US) 2021-04-29 US claimed
WO-2021067326-A1 SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2021-04-08 WO claimed
US-10881608-B2 Biodegradable intravitreal tyrosine kinase implants ALLERGAN, INC. (US) 2021-01-05 US claimed
CN-109923114-A Pyrazolopyridine derivatives as HPK1 modulators and their use for the treatment of cancer 因赛特公司 2019-06-21 CN claimed
EP-3008055-B1 TETRAZOLONE DERIVATIVES HOFFMANN LA ROCHE (CH) 2017-07-19 EP claimed
EP-3008055-A1 NOVEL TETRAZOLONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2016-04-20 EP claimed
US-20160083357-A1 NOVEL TETRAZOLONE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2016-03-24 US claimed
WO-2014198592-A1 NOVEL TETRAZOLONE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2014-12-18 WO claimed
US-20120301426-A1 ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2012-11-29 US claimed
EP-2432784-A1 FUSED BICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS UCB Pharma, S.A. (BE) 2012-03-28 EP claimed
US-20100310500-A1 ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-12-09 US claimed
WO-2010133836-A1 FUSED BICYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2010-11-25 WO claimed
US-20070249847-A1 Method for Producing Acetamidopyrrolidine Derivatives and Intermediate Compounds Thereof TEIJIN PHARMA LIMITED (JP) 2007-10-25 US claimed
EP-1760075-A1 METHOD FOR PRODUCING ACETAMIDOPYRROLIDINE DERIVATIVE AND INTERMEDIATE COMPOUND THEREOF Teijin Pharma Limited (JP) 2007-03-07 EP claimed
CN-1085893-A Process for preparing pyrrolidinylacetamide derivatives DAIICHI SEIYAKU CO (JP) 1994-04-27 CN claimed
JP-51133287-A None JP disclosed
JP-S51133287-A A PROCESS FOR PREPARING QUINAZOLONEACETIC ACID AMIDE DERIVATIVES TANABE SEIYAKU CO LTD 1976-11-18 JP disclosed