Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123494 | 1.00 | HTT (0.45) | HTTL3MBTL1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL715894 | 0.97 | — | — | |
| SCHEMBL19052251 | 0.92 | — | — | |
| SCHEMBL29107984 | 0.90 | CA2 (0.41) | HTTL3MBTL1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL8033657 | 0.87 | HTT (0.50) | HTTL3MBTL1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL9613513 | 0.86 | — | — | |
| Trifluoroacetic Acid SCHEMBL6218638 | 0.83 | HTT (0.38) | HTTL3MBTL1ALDH1A1CYP3A4KDM4E | |
| SCHEMBL27412940 | 0.81 | HTT (0.49) | HTTALDH1A1CYP3A4KDM4EGAA | |
| SCHEMBL14500231 | 0.80 | CA12 (0.53) | HTTGAALIPEMEN1KMT2A | |
| SCHEMBL4685447 | 0.78 | HTT (0.31) | HTTL3MBTL1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038589-A1 | USES, COMPOSITIONS AND METHODS | FISAHN ANDRE (SE) | 2021-02-11 | — | — | US | claimed |
| EP-3765082-A1 | USES, COMPOSITIONS AND METHODS | Fisahn, André (SE) | 2021-01-20 | — | — | EP | claimed |
| WO-2019175395-A1 | USES, COMPOSITIONS AND METHODS | FISAHN ANDRE (SE) | 2019-09-19 | — | — | WO | claimed |
| CN-109575045-A | Thienopyrimidines, preparation method, Pharmaceutical composition and its application | 南京红云生物科技有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-107698603-A | Thienopyrimidines, its preparation method, Pharmaceutical composition and its application | 厦门大学 | 2018-02-16 | — | — | CN | claimed |
| EP-1506961-B1 | Processes for resolving piperidyl acetamide stereoisomers | CELGENE CORP (US) | 2012-02-22 | — | — | EP | claimed |
| EP-1265866-B1 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-07-21 | — | — | EP | claimed |
| US-7459560-B2 | Processes and intermediates for resolving piperidyl acetamide stereoisomers | CELGENE CORPORATION (US) | 2008-12-02 | — | — | US | claimed |
| US-20060142583-A1 | Processes and intermediates for resolving piperidyl acetamide stereoisomers | KHETANI VIKRAM | 2006-06-29 | — | — | US | claimed |
| US-6962997-B1 | Process and intermediates for resolving piperidyl acetamide steroisomers | CELGENE CORPORATION (US) | 2005-11-08 | — | — | US | claimed |
| EP-0983238-B1 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORP (US) | 2004-08-18 | — | — | EP | claimed |
| EP-0690889-B1 | LIGHT STABILIZER PACKAGES FOR PARTIAL PAINT APPLICATIONS | SOLVAY ENGINEERED POLYMERS (US) | 2002-07-31 | — | — | EP | claimed |
| US-6359139-B1 | REACTING 1-THREO-PIPERIDYL ACETAMIDE WITH AN ALKANOIC ACID IN SOLVNET | CELGENE CORPORATION | 2002-03-19 | — | — | US | claimed |
| EP-0983238-A4 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORP (US) | 2001-08-08 | — | — | EP | claimed |
| US-6051637-A | MOLDED COMPOSITION THAT DOES NOT INTERFER WITH ACID CURATIVE COATINGS OF THERMOPLASTIC POLYOLEFIN, MONOMERIC AND POLYMERIC HINDERED AMINE LIGHT STABILIZER(HALS) HAVING A PKA OF NO GREATER THAN 7, AND AN ULTRAVIOLET LIGHT ABSORBER | SOLVAY ENGINEERED POLYMERS (US) | 2000-04-18 | — | — | US | claimed |
| EP-0983238-A1 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORPORATION (US) | 2000-03-08 | — | — | EP | claimed |
| US-5936091-A | Processes and intermediates for resolving piperidyl acetamide stereoisomers | CELGENE CORPORATION (US) | 1999-08-10 | — | — | US | claimed |
| WO-1998052921-A1 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORPORATION (US) | 1998-11-26 | — | — | WO | claimed |
| US-5733956-A | COMPRISES A THERMOPLASTIC OLEFIN, A MONOMERIC AND A POLYMERIC HINDERED AMINE LIGHT STABILIZER AND AN ULTRAVIOLET LIGHT ABSORBING BENZOTRIAZOLE | SOLVAY ENGINEERED POLYMERS (US) | 1998-03-31 | — | — | US | claimed |
| EP-0188805-B1 | 1,3-DITHIOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038589-A1 | USES, COMPOSITIONS AND METHODS | APP, CACNA1G, CACNA1B | HTT 146/4885L3MBTL1 4840/4885ALDH1A1 2709/4885 |
| US-20060142583-A1 | Processes and intermediates for resolving piperidyl acetamide stereoisomers | NAAA, DHPS, CTPS2 | HTT 2993/4885L3MBTL1 4536/4885ALDH1A1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.