SCHEMBL7159141

SCHEMBL7159141

C=Cc1ccc2c(c1)CCCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.40
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
STS P08842 1/20 0.37
SRD5A1 P18405 1/20 0.36
TP53 P04637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33130 0.95 ALDH1A1 (0.43) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL1697578 0.91 ALDH1A1 (0.48) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL29475832 0.91 ALDH1A1 (0.48) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL31122823 0.91 ALDH1A1 (0.48) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL6898460 0.77 TSHR (0.40) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL1525600 0.77 ALDH1A1 (0.53) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL30786494 0.76
SCHEMBL5958010 0.76 ALDH1A1 (0.51) ALDH1A1TSHRADRA2AADRA2BADRA2C
SCHEMBL3297666 0.74 ALDH1A1 (0.46) ALDH1A1TSHRSRD5A1TP53TDP1
SCHEMBL22187693 0.74 ALDH1A1 (0.46) ALDH1A1TSHRADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953421-B1 Process for the preparation of end-products based on vinylaromatic polymers with a predominantly syndiotactic structure POLIMERI EUROPA SRL (IT) 2003-11-05 EP disclosed
EP-0994126-B1 Process for the preparation of vinylaromatic polymers with a high degree of syndiotacticity POLIMERI EUROPA SPA (IT) 2003-07-09 EP disclosed
EP-0857555-B1 Process for the preparation of manufactured products based on vinylaromatic polymers with a predominantly syndiotactic structure ENICHEM SPA (IT) 2002-02-27 EP disclosed
US-6342573-B1 COMPRESSING TO POWDER, SINTERING UNDER HIGH PRESSURE, COOLING; CATALYTIC ADDITION POLYMERIZATION; RECOVERING BY PRECIPITATION AND FILTRATION; DRYING ENICHEM S.P.A. (IT) 2002-01-29 US disclosed
US-6184316-B1 AS POLYMERIZATION CATALYST; EFFICIENCY ENICHEM S.P.A. (IT) 2001-02-06 US disclosed
US-6174973-B1 COMPLEX OF TITANIUM, ALUMINOXANE AND ALUMINUM FLUORIDE ENICHEM S.P.A. (IT) 2001-01-16 US disclosed
EP-1059082-A1 Use of substituted vinyltetrahydronaphthalenes and vinylbenzotetrahydropyrans as sunscreens BASF AKTIENGESELLSCHAFT (DE) 2000-12-13 EP disclosed
US-6066706-A Process for the preparation of crystalline vinylaromatic polymers with a predominately syndiotactic structure ENICHEM S.P.A. (IT) 2000-05-23 US disclosed
US-6066280-A COMPRESSING IN POWDER FORM IN A MOLD AT A PRESSURE RANGING FROM 0.1 TO 500 MPA; SINTERING, UNDER PRESSURE, THE COMPACT POWDER AT A TEMPERATURE RANGING FROM THE GLASS TRANSITION TEMPERATURE OF THE POLYMER TO THE MELTING TEMPERATURE ENICHEM S.P.A. (IT) 2000-05-23 US disclosed
EP-0994126-A1 Process for the preparation of vinylaromatic polymers with a high degree of syndiotacticity Enichem S.p.A. (IT) 2000-04-19 EP disclosed
EP-0271874-B1 PROCESS FOR PRODUCING CRYSTALLINE VINYL AROMATIC POLYMERS HAVING A PREDOMINANTLY SYNDIOTACTIC STRUCTURE Montedison S.p.A. (IT) 1992-10-14 EP disclosed
US-5142005-A Using coordination polymerization catalysts MONTEDISON S.P.A. (IT) 1992-08-25 US disclosed
EP-0272584-A2 Process for producing crystalline vinyl aromatic polymers having a predominantly syndiotactic structure Montedison S.p.A. (IT) 1988-06-29 EP disclosed
EP-0271875-A2 Process for producing crystalline vinyl aromatic polymers having a predominantly syndiotactic structure Montedison S.p.A. (IT) 1988-06-22 EP disclosed
EP-0271874-A2 Process for producing crystalline vinyl aromatic polymers having a predominantly syndiotactic structure Montedison S.p.A. (IT) 1988-06-22 EP disclosed
US-4551502-A Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics HOWELL BOBBY A 1985-11-05 US disclosed
US-4405757-A Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics HOWELL BOBBY A 1983-09-20 US disclosed
US-4156764-A Poly(hydroxy) telechelic styrene polymer process GENERAL ELECTRIC COMPANY (US) 1979-05-29 US disclosed
US-4146697-A POLY(ORGANOSILOXY) TELECHELIC STYRENE POLYMER PROCESS GENERAL ELECTRIC COMPANY (US) 1979-03-27 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed