Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27877854 | 0.95 | ALDH1A1 (0.41) | TSHRADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL1525600 | 0.77 | ALDH1A1 (0.53) | TSHRADRA2AADRA2BADRA2CSTS | |
| SCHEMBL7159141 | 0.77 | ALDH1A1 (0.43) | TSHRADRA2AADRA2BADRA2CSTS | |
| SCHEMBL5958010 | 0.76 | ALDH1A1 (0.51) | TSHRADRA2AADRA2BADRA2CSTS | |
| SCHEMBL33130 | 0.73 | ALDH1A1 (0.43) | TSHRADRA2AADRA2BADRA2CSTS | |
| SCHEMBL7512041 | 0.73 | ALDH1A1 (0.53) | TSHRSTSALDH1A1MEN1GAA | |
| SCHEMBL1525801 | 0.73 | ALDH1A1 (0.53) | TSHRSTSALDH1A1MEN1GAA | |
| SCHEMBL29942408 | 0.73 | ALDH1A1 (0.53) | TSHRSTSALDH1A1MEN1GAA | |
| SCHEMBL12745318 | 0.72 | MAPK1 (0.48) | ADRA2AADRA2BADRA2CTRPV1ALDH1A1 | |
| SCHEMBL12745011 | 0.72 | ALDH1A1 (0.46) | TSHRADRA2AADRA2BADRA2CSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |
| US-20180199575-A1 | SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | US | disclosed |
| EP-3051946-B1 | USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AG (DE) | 2017-11-29 | — | — | EP | disclosed |
| EP-1023044-B1 | APATITE-COATED SOLID COMPOSITION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-04 | — | — | EP | disclosed |
| US-20030185878-A1 | Process for producing phospholipid-containing drug | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6552054-B1 | For prophylaxis and therapy of bone diseases and chondropathy | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1293197-A1 | PROCESS FOR PRODUCING PHOSPHOLIPID-CONTAINING DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6531604-B2 | Useful as medicines having an osteogenesis promoting effect and chondrogensis promoting effect. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-11 | — | — | US | disclosed |
| US-6022564-A | Method for producing a microparticle | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-08 | — | — | US | disclosed |
| WO-1999065474-A2 | COMPOSITIONS FOR TREATING CARTILAGE DISEASE COMPRISING CERTAIN SULFUR-CONTAINING HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-23 | — | — | WO | disclosed |
| EP-0949927-A2 | PHARMACEUTICAL COMPOSITION CONTAINING OSTEOGENESIS-PROMOTING SUBSTANCE AND A POLYETHYLENE GLYCOL | Takeda Chemical Industries, Ltd. (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0930874-A2 | A METHOD FOR PRODUCING A MICROPARTICLE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5910492-A | PREVENTION AND TREATMENT OF BONE DISEASES, REPAIR OF BONE TISSUE, REGENERATION OF PERIODONTAL TISSUE; SHORTENED HEALING TIME | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| WO-1998047485-A2 | APATITE-COATED SOLID COMPOSITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998015263-A2 | A METHOD FOR PRODUCING A MICROPARTICLE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |
| EP-0831808-A1 | OSTEOGENETIC PROMOTING PHARMACEUTICAL COMPOSITION | Takeda Chemical Industries, Ltd. (JP) | 1998-04-01 | — | — | EP | disclosed |
| WO-1998008517-A2 | PHARMACEUTICAL COMPOSITION CONTAINING OSTEOGENESIS-PROMOTING SUBSTANCE AND A POLYETHYLENE GLYCOL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |
| WO-1996039134-A1 | OSTEOGENETIC PROMOTING PHARMACEUTICAL COMPOSITION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185878-A1 | Process for producing phospholipid-containing drug | PHOSPHO1, PLTP, PTDSS2 | TSHR 3530/4885ADRA2A 1585/4885ADRA2B 1669/4885 |
| US-20180199575-A1 | SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | PPA1, PHOSPHO1, PIP4K2C | TSHR 4223/4885ADRA2A 4535/4885ADRA2B 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.