Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.62 |
| ▸ | ACACA | Q13085 | 1/20 | 0.62 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918764 | 1.00 | ACACB (0.62) | ACACBACACARIPK1PPARAACLY | |
| Bempedoic Acid SCHEMBL6184385 | 0.83 | ACACB (0.75) | ACACBACACAPPARAACLYLTB4R | |
| SCHEMBL2737000 | 0.81 | RIPK1 (0.56) | ACACBACACARIPK1PPARAACLY | |
| SCHEMBL11121881 | 0.81 | ACACB (0.50) | ACACBACACAPPARAACLYLTB4R | |
| SCHEMBL11098393 | 0.81 | ACACB (0.50) | ACACBACACAPPARAACLYLTB4R | |
| SCHEMBL30444239 | 0.81 | ACACB (0.49) | ACACBACACARIPK1PPARAACLY | |
| SCHEMBL29015074 | 0.81 | ACACB (0.49) | ACACBACACARIPK1PPARAACLY | |
| SCHEMBL27360178 | 0.79 | PPARA (0.48) | ACACBACACARIPK1PPARALTB4R | |
| SCHEMBL15006719 | 0.78 | RIPK1 (0.52) | RIPK1LMNA | |
| SCHEMBL23348922 | 0.77 | ACACB (1.00) | ACACBACACAACLYTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940383-B1 | Method for the selective alkylation of aldehydes with organozinc compounds | CHEMETALL GMBH (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-6184404-B1 | THE ORGANOZINC COMPOUND HAVING A LIGAND WHICH IS TRANSFERRED TO THE ALDEHYDE, THE OTHER LIGAND ACTS AS SO-CALLED DUMMY LIGAND; PRODUCING FUNCTIONALIZED SECONDARY ALCOHOLS IN GOOD YIELDS AND VERY GOOD ENANTIOMERIC PURITY; MATERIALS HANDLING | METALLGESELLSCHAFT AKTIENGESELLSCHAFT (DE) | 2001-02-06 | — | — | US | disclosed |
| EP-0940383-A2 | Method for the selective alkylation of aldehydes with organozinc compounds | Metallgesellschaft Aktiengesellschaft (DE) | 1999-09-08 | — | — | EP | disclosed |