Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908799 | 0.86 | RIPK1 (0.53) | TBXAS1CYP2C19RIPK1CNR1CNR2 | |
| SCHEMBL15474468 | 0.83 | RIPK1 (0.50) | TBXAS1CYP2C19RIPK1CNR1CNR2 | |
| SCHEMBL27741741 | 0.82 | RIPK1 (0.49) | TBXAS1CYP2C19RIPK1CNR1CNR2 | |
| SCHEMBL14360139 | 0.80 | TBXAS1 (0.60) | TBXAS1CYP2C19 | |
| SCHEMBL455432 | 0.79 | POLB (0.53) | TBXAS1CYP2C19CNR2SMN1; SMN2 | |
| SCHEMBL7159146 | 0.79 | ACACB (0.62) | PPARAACACBACACATBXAS1RIPK1 | |
| SCHEMBL7918764 | 0.79 | ACACB (0.62) | PPARAACACBACACATBXAS1RIPK1 | |
| SCHEMBL30444239 | 0.79 | ACACB (0.49) | PPARAACACBACACATBXAS1RIPK1 | |
| SCHEMBL29015074 | 0.79 | ACACB (0.49) | PPARAACACBACACATBXAS1RIPK1 | |
| Ammonia Solution, Strong SCHEMBL28562956 | 0.78 | TBXAS1 (0.59) | TBXAS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056680-A | The preparation method who can be used as the 2-phenylalkanoic acid esters of human leukocytes elastase inhibitor | CORTECH INC (US) | 1991-12-04 | — | — | CN | disclosed |