Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747266 | 0.90 | DRD2 (0.49) | DRD2HTR6SLC5A1SLC5A2HRH2 | |
| SCHEMBL7703139 | 0.84 | HRH2 (0.50) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6870957 | 0.83 | HRH2 (0.61) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6777709 | 0.82 | LMNA (0.56) | DRD2HTR6SLC5A1SLC5A2HRH2 | |
| SCHEMBL7154548 | 0.82 | HRH2 (0.51) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6777121 | 0.78 | DRD2 (0.62) | DRD2HTR6SLC5A1SLC5A2HRH2 | |
| SCHEMBL20431459 | 0.77 | SLC2A1 (0.57) | SLC5A1SLC5A2HRH2HTR2AHTR2C | |
| SCHEMBL6780420 | 0.76 | DRD2 (0.59) | DRD2HTR6SLC5A1SLC5A2HRH2 | |
| SCHEMBL27493414 | 0.74 | SLC5A1 (0.56) | DRD2HTR6SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL6775869 | 0.74 | HRH2 (0.62) | DRD2HTR6SLC5A1SLC5A2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003501424-A | — | — | 2003-01-14 | — | — | JP | claimed |
| EP-1183251-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2002-03-06 | — | — | EP | claimed |
| WO-2000075130-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-12-14 | — | — | WO | claimed |