Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.49 |
| ▸ | HNF4A | P41235 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914142 | 0.80 | RXRA (0.45) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6874366 | 0.79 | RXRA (0.49) | RXRAHNF4APPARGNR1H3THRA | |
| SCHEMBL6915028 | 0.79 | RXRA (0.49) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6479338 | 0.78 | RXRA (0.47) | RXRAHNF4APPARGNR1H3THRA | |
| SCHEMBL13240539 | 0.78 | THRA (0.43) | RXRAPPARGTHRATHRB | |
| SCHEMBL6032593 | 0.77 | RXRA (0.47) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6917087 | 0.76 | RXRA (0.51) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6913948 | 0.76 | RXRA (0.57) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6917792 | 0.76 | RXRA (0.57) | RXRAHNF4APPARGNR1H3RARA | |
| SCHEMBL6472792 | 0.75 | RXRA (0.48) | RXRAHNF4APPARGNR1H3RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545049-B1 | E.g., (2E, 4E, 6E)-7-(3,5-diisopropyl-2-n-heptyloxyphenyl)-3-methylocta-2,4,6-trienoic acid, esters or amides thereof | LIGAND PHARMACEUTICALS INCORPORATED | 2003-04-08 | — | — | US | disclosed |