SCHEMBL7159408

SCHEMBL7159408

Cc1c(C(=O)Oc2ccnn2C)ccc2snnc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7154413 0.81 KDM4E (0.32) ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL7158409 0.77 MAPT (0.38) ALDH1A1MAPTKDM4EHPGD
SCHEMBL12602534 0.72 SMN1; SMN2 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL6986066 0.72 THRB (0.36) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL7156589 0.71
SCHEMBL6979351 0.71
SCHEMBL30293897 0.68 NAMPT (0.44) ALDH1A1MAPTSMN1; SMN2
SCHEMBL10959724 0.67 MAPT (0.53) ALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL3427273 0.65 SMN1; SMN2 (0.40) ALDH1A1SMN1; SMN2
SCHEMBL27359663 0.65 HTT (0.42) ALDH1A1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed