Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290189 | 1.00 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL6785174 | 0.88 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL5884005 | 0.87 | PTGS2 (0.69) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL5884009 | 0.87 | PTGS2 (0.69) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL27851648 | 0.86 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL26445244 | 0.86 | ABCG2 (0.64) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL1877390 | 0.85 | ABCG2 (0.68) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL1877387 | 0.85 | ABCG2 (0.68) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA | |
| SCHEMBL29048769 | 0.85 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2ABCG2PTGS2AURKA | |
| SCHEMBL23122299 | 0.84 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2ABCG2PTGS2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427443-B1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GMBH (DE) | 2014-10-15 | — | — | EP | disclosed |
| US-8598228-B2 | Cinnamic acid ascorbates | MERCK PATENT GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-01 | — | — | US | disclosed |
| WO-2010127756-A1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GMBH (DE) | 2010-11-11 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4230696-A | CONTAINING GLYCINE AND LYSINE OR ARGININE | ST. LUKE'S HOSPITAL (US) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | PROC, C1S, NISCH | ALDH1A1 16/4885SMN1; SMN2 3843/4885ABCG2 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.