Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.62 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.57 |
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 6/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611244 | 0.89 | HINT1 (0.77) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL6363921 | 0.85 | HINT1 (0.65) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL7151774 | 0.84 | HINT1 (0.63) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5663210 | 0.83 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL4733243 | 0.83 | HINT1 (0.76) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL8450059 | 0.81 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL6397385 | 0.81 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL2337631 | 0.81 | HINT1 (0.61) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL10446658 | 0.80 | PNP (0.58) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL217117 | 0.80 | HINT1 (0.80) | HINT1GSK3ARPS6KA3MAPK14PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187240-A1 | 2' -modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | disclosed |
| US-20030004325-A1 | Sugar modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2003-01-02 | — | — | US | disclosed |
| US-6399754-B1 | CONTAINING SULFOPHOSPHATE GROUP | ISIS PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |