Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.73 |
| ▸ | GSK3A | P49840 | 2/20 | 0.67 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.67 |
| ▸ | PNP | P00491 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.63 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 6/20 | 0.57 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733243 | 0.93 | HINT1 (0.76) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL1611244 | 0.92 | HINT1 (0.77) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL217117 | 0.88 | HINT1 (0.80) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| E626 SCHEMBL4801526 | 0.87 | NT5E (0.72) | HINT1NT5ETGM2KRASFUT5 | |
| SCHEMBL1138806 | 0.86 | HINT1 (0.71) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL10681529 | 0.86 | HINT1 (0.69) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL6899834 | 0.85 | HINT1 (0.68) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL8445552 | 0.85 | HINT1 (0.58) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL9295418 | 0.85 | HINT1 (0.75) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL9295421 | 0.85 | HINT1 (0.75) | HINT1GSK3ARPS6KA3MAPK14PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |