Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 15/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 15/20 | 0.68 |
| ▸ | GAK | O14976 | 2/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377512 | 0.82 | PIK3CD (0.73) | PDGFRBPDGFRAGAKPIK3CDPIK3CA | |
| SCHEMBL31060782 | 0.81 | PDGFRB (1.00) | PDGFRBPDGFRA | |
| SCHEMBL24253008 | 0.79 | MEN1 (0.53) | PDGFRBPDGFRAGAKKDM4EALDH1A1 | |
| SCHEMBL8500090 | 0.78 | PDGFRB (0.55) | PDGFRBPDGFRAPIK3CAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7162831 | 0.75 | KDM4E (0.65) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL30467740 | 0.75 | PDGFRB (0.44) | PDGFRBPDGFRAGAKKDM4EALDH1A1 | |
| SCHEMBL24252628 | 0.75 | PDGFRB (0.44) | PDGFRBPDGFRAGAKKDM4EALDH1A1 | |
| SCHEMBL7153198 | 0.75 | S1PR1 (0.57) | PDGFRBPDGFRAGAK | |
| Hydrochloric Acid SCHEMBL7157628 | 0.74 | PDGFRB (0.69) | PDGFRBPDGFRAGAKPIK3CDPIK3CA | |
| SCHEMBL26771362 | 0.74 | PDGFRB (0.43) | PDGFRBPDGFRAGAKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030004165-A1 | Polyazanaphthalene compounds and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004165-A1 | Polyazanaphthalene compounds and pharmaceutical use thereof | MMP1, TNF, MMP12 | PDGFRB 663/4885PDGFRA 1117/4885GAK 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.