Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21197485 | 0.98 | ALDH1A1 (0.37) | NOS2NOS3NOS1ALDH1A1HRH4 | |
| SCHEMBL28693236 | 0.94 | ALDH1A1 (0.40) | NOS2NOS3NOS1ALDH1A1HRH4 | |
| SCHEMBL7508980 | 0.86 | CHRNB2 (0.36) | NOS2NOS3NOS1ALDH1A1HRH4 | |
| Hydrochloric Acid SCHEMBL21197508 | 0.84 | CHRNB2 (0.35) | NOS2NOS3NOS1ALDH1A1TDP1 | |
| SCHEMBL15340966 | 0.81 | BLM (0.44) | CYP1A2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13368999 | 0.80 | BLM (0.52) | NOS2NOS3NOS1ALDH1A1CYP1A2 | |
| SCHEMBL11256507 | 0.80 | CA1 (0.48) | NOS2NOS3NOS1ALDH1A1HRH4 | |
| SCHEMBL28060820 | 0.80 | USP2 (0.40) | ALDH1A1TSHRUSP2HTR2AHRH1 | |
| SCHEMBL8588686 | 0.80 | BLM (0.52) | NOS2NOS3NOS1ALDH1A1CYP1A2 | |
| SCHEMBL9763558 | 0.79 | CA1 (0.44) | NOS2ALDH1A1CA1CA2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146764-A | Metabolites of 2-arylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG (IT) | 2008-03-19 | — | — | CN | claimed |
| EP-3997079-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021004498-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-01-14 | — | — | WO | disclosed |
| EP-3743412-A1 | GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019144864-A1 | GLUCOPYRANOSYL DERIVATIVE AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-08-01 | — | — | WO | disclosed |
| CN-101146764-A | Metabolites of 2-arylpropionic acid derivatives and pharmaceutical compositions containing them | DOMPE PHA R MA SPA RES & MFG (IT) | 2008-03-19 | — | — | CN | disclosed |
| EP-1366018-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.P.A. (IT) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002068377-A1 | OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE AND MONONUCLEATE CELLS | Dompé S.p.A. (IT) | 2002-09-06 | — | — | WO | disclosed |