Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245694 | 0.88 | NPC1 (0.65) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9638630 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8080634 | 0.86 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8645132 | 0.85 | SMN1; SMN2 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10501291 | 0.84 | ALDH1A1 (0.40) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9494867 | 0.82 | MAPT (0.35) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10482330 | 0.82 | NPC1 (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8586984 | 0.81 | RARB (0.55) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL10505271 | 0.81 | NPC1 (0.36) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9018434 | 0.80 | RAB9A (0.39) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025119-B1 | NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1983-05-25 | — | — | EP | claimed |
| EP-0025119-A1 | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1981-03-18 | — | — | EP | claimed |
| JP-4089483-A | — | — | None | — | — | JP | disclosed |
| JP-8291148-A | — | — | None | — | — | JP | disclosed |
| JP-6298760-A | — | — | None | — | — | JP | disclosed |
| JP-4297462-A | — | — | None | — | — | JP | disclosed |
| JP-4316562-A | — | — | None | — | — | JP | disclosed |
| JP-63253074-A | — | — | None | — | — | JP | disclosed |
| JP-6306055-A | — | — | None | — | — | JP | disclosed |
| JP-63165371-A | — | — | None | — | — | JP | disclosed |
| JP-63295564-A | — | — | None | — | — | JP | disclosed |
| US-4786730-A | Pyrimidine compound | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1988-11-22 | — | — | US | disclosed |
| JP-S63253074-A | PYRIMIDINE COMPOUND | ADEKA ARGUS CHEM CO LTD | 1988-10-20 | — | — | JP | disclosed |
| EP-0285395-A1 | Phenyl-pyrimidine liquid crystal compounds and liquid crystal compositions containing the same | AJINOMOTO CO., INC. (JP) | 1988-10-05 | — | — | EP | disclosed |
| JP-S63165371-A | PYRIMIDINE COMPOUND | ADEKA ARGUS CHEM CO LTD | 1988-07-08 | — | — | JP | disclosed |
| JP-S6124576-A | LIQUID CRYSTAL COMPOUND | SEIKO INSTR & ELECTRONICS LTD | 1986-02-03 | — | — | JP | disclosed |
| US-4405500-A | DURABILITY | EC ERDOLCHEMIE GMBH (DE) | 1983-09-20 | — | — | US | disclosed |
| EP-0025119-B1 | NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1983-05-25 | — | — | EP | disclosed |
| US-4311610-A | Liquid crystalline 5-alkyl-2 (4-acyloxy-phenyl)-pyrimidine | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1982-01-19 | — | — | US | disclosed |
| EP-0025119-A1 | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1981-03-18 | — | — | EP | disclosed |