Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489476 | 0.90 | TSHR (0.44) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL4628294 | 0.87 | TSHR (0.48) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL4628173 | 0.87 | TSHR (0.48) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL29672148 | 0.86 | ALDH1A1 (0.58) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Dibutyl Phthalate SCHEMBL29658281 | 0.86 | TSHR (0.64) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| Dibutyl Phthalate SCHEMBL9183712 | 0.85 | ALDH1A1 (0.53) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| Phthalic Acid SCHEMBL31462355 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBCA2 | |
| Phthalic Acid SCHEMBL29113646 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10POLBCA2 | |
| Dibutyl Phthalate SCHEMBL8359408 | 0.83 | TSHR (0.59) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL29433637 | 0.82 | PRSS1 (0.48) | TSHRTDP1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544920-B1 | Efficiency; to produce polymers having a higher bulk density | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-04-08 | — | — | US | disclosed |
| EP-0811021-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL NORTH AMERICA INC (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0811021-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montell North America Inc. (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1997023518-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | MONTELL NORTH AMERICA INC. (US) | 1997-07-03 | — | — | WO | disclosed |