SCHEMBL18489476

SCHEMBL18489476

CCCCOC(=O)c1c(C(=O)O)ccc(CC(C)C)c1CC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 6/20 0.41
MAPK1 P28482 4/20 0.41
CYP3A4 P08684 3/20 0.41
TP53 P04637 1/20 0.40
HSD17B10 Q99714 2/20 0.40
LMNA P02545 3/20 0.40
ESR1 P03372 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP2D6 P10635 1/20 0.40
NR1H2 P55055 1/20 0.40
RNASEL Q05823 1/20 0.40
CYP2C9 P11712 1/20 0.39
PDE4D Q08499 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18489638 0.92 ALDH1A1 (0.42) TSHRTDP1L3MBTL1ALDH1A1MAPK1
Dibutyl Phthalate SCHEMBL7159902 0.90 TSHR (0.56) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL4628294 0.85 TSHR (0.48) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL4628173 0.85 TSHR (0.48) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL18489550 0.81 CDK4 (0.38) ALDH1A1MAPK1HSD17B10LMNASMN1; SMN2
SCHEMBL4627968 0.80 TSHR (0.48) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL77326 0.79 LMNA (0.39) TSHRALDH1A1LMNAESR1SMN1; SMN2
SCHEMBL4627152 0.79 TSHR (0.47) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL4628808 0.79 TSHR (0.47) TSHRTDP1L3MBTL1ALDH1A1MAPK1
SCHEMBL4627123 0.79 TSHR (0.47) TSHRTDP1L3MBTL1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US disclosed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP disclosed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US disclosed