Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522264 | 0.79 | — | — | |
| Water SCHEMBL7165823 | 0.71 | GRIA1 (0.50) | — | |
| SCHEMBL7374814 | 0.71 | TP53 (0.43) | NPC1RAB9AHSD17B10 | |
| SCHEMBL7374475 | 0.68 | HTR2A (0.41) | HTR2AHTR2CCHRM3CHRM2CHRM4 | |
| SCHEMBL7375751 | 0.68 | ADORA3 (0.38) | HTR2AHTR2CCHRM3NPC1RAB9A | |
| SCHEMBL7370168 | 0.67 | KDM4E (0.46) | NPC1RAB9AHSD17B10 | |
| SCHEMBL7161588 | 0.63 | KDM4E (0.36) | HTR2AHTR2CCHRM3CHRM2CHRM4 | |
| SCHEMBL7366104 | 0.62 | HTR2A (0.37) | HTR2AHTR2CCHRM3CHRM2CHRM4 | |
| SCHEMBL31226204 | 0.61 | HTT (0.36) | CHRM3NPC1RAB9ACHRM2CHRM4 | |
| SCHEMBL7165046 | 0.61 | HTR2A (0.36) | HTR2AHTR2CCHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934286-B1 | 3-ALKOXYISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS | LUNDBECK & CO AS H (DK) | 2003-01-08 | — | — | EP | disclosed |
| US-6200999-B1 | ALZHEIMER*S, HUNTINGTON*S, AND PARKINSON*S DISEASE; ANTIEPILEPTIC, ANALGESIC, ANXIOLYTIC, ANTIISCHEMIC AND ANTIDEPRESSANT AGENTS; NMDA AND AMPA RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2001-03-13 | — | — | US | disclosed |