Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832971 | 1.00 | KDM4E (0.48) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL2889939 | 0.87 | TRPV1 (0.47) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL17455924 | 0.85 | TRPV1 (0.46) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL30098846 | 0.83 | KDM4E (0.48) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL7036968 | 0.83 | KDM4E (0.48) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL5144683 | 0.82 | CYP2A6 (0.58) | KDM4ELMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL3719145 | 0.82 | TRPV1 (0.47) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL4049174 | 0.82 | TRPV1 (0.47) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL31692108 | 0.81 | KDM4E (0.39) | KDM4EL3MBTL1LMNAGAANPC1 | |
| SCHEMBL8192202 | 0.80 | DPP4 (0.50) | KDM4EL3MBTL1LMNAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548836-B1 | Solid state light-emitting device | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-04-15 | — | — | US | disclosed |
| EP-0411935-A2 | Copper radio sensitizers | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-02-06 | — | — | EP | disclosed |