SCHEMBL7160892

SCHEMBL7160892

C=CC(=O)OC(C)(OC(=O)C=C)OC(=O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.32
ALDH1A1 P00352 4/20 0.31
TP53 P04637 3/20 0.31
HIF1A Q16665 3/20 0.31
CYP3A4 P08684 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4907178 0.78 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7162567 0.78 HCAR2 (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7167884 0.78 HCAR2 (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7162573 0.78 HCAR2 (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
Hydrogen Peroxide SCHEMBL27482921 0.75 LMNA (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7166529 0.75 HSD17B10 (0.34) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7165645 0.74 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7166492 0.74 ALDH1A1 (0.42) TSHRALDH1A1THRB
SCHEMBL7165101 0.73 EGLN1 (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28920330 0.72 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6558740-B1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 2003-05-06 US disclosed
EP-0741045-B1 Printing medium, production process thereof and image-forming process using the medium CANON KK (JP) 1999-10-27 EP disclosed
US-5965252-A SUBSTRATE AND INK-RECEIVING LAYER COMPRISING ALUMINA HYDRATE SURFACE TREATED WITH A COUPLING AGENT TO MAKE IT MORE HYDROPHOBIC; FOR WATER BASED INKS; PREVENTS BEADING, PROVIDES IMAGES HIGH IN OPTICAL DENSITY, SURFACE HARDNESS CANON KABUSHIKI KAISHA (JP) 1999-10-12 US disclosed
EP-0741045-A1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed