Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 14/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7161168 | 0.91 | ALDH1A1 (0.40) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL7159960 | 0.90 | ALDH1A1 (0.39) | ALDH1A1NPC1ABCB1 | |
| SCHEMBL7161077 | 0.87 | ALDH1A1 (0.39) | ALDH1A1NPC1ABCB1 | |
| SCHEMBL7205212 | 0.81 | ALDH1A1 (0.39) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL14615902 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPC1ABCB1 | |
| SCHEMBL15075166 | 0.79 | ALDH1A1 (0.43) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL12111919 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPC1ABCB1 | |
| SCHEMBL12112020 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPC1ABCB1 | |
| SCHEMBL8427134 | 0.79 | POLB (0.39) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL7161805 | 0.78 | POLB (0.41) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| US-5763418-A | NUCLEOTIDE ANTITUMOR AGENTS | Matsuda, Akira (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |