Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744950 | 0.85 | TYR (0.54) | TYRAKR1B10AKR1B1THRBTAAR1 | |
| SCHEMBL716321 | 0.85 | TYR (0.54) | TYRAKR1B10AKR1B1THRBTAAR1 | |
| SCHEMBL30775445 | 0.83 | THRB (0.57) | TYRAKR1B10AKR1B1THRBTAAR1 | |
| SCHEMBL961984 | 0.83 | THRB (0.57) | TYRAKR1B10AKR1B1THRBTAAR1 | |
| SCHEMBL4354447 | 0.77 | THRB (0.54) | AKR1B10AKR1B1THRBALOX5TSHR | |
| SCHEMBL716183 | 0.77 | THRB (0.33) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27539720 | 0.76 | THRB (0.45) | TYRTHRBTSHRALDH1A1POLB | |
| SCHEMBL27530889 | 0.76 | THRB (0.54) | TYRAKR1B10AKR1B1THRBTAAR1 | |
| Dopamine SCHEMBL23210259 | 0.75 | MAPK1 (0.50) | TAAR1TSHRALDH1A1TP53HIF1A | |
| SCHEMBL31033071 | 0.75 | TSHR (0.51) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053287-A1 | RESIN COMPOSITION FOR INSULATING LAYER | SUMITOMO CHEMICAL COMPANY, LTD (JP) | 2012-03-01 | — | — | US | disclosed |