Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | TTR | P02766 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426103 | 0.92 | THRB (0.68) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL31404677 | 0.92 | THRB (0.68) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Methacrylic Acid SCHEMBL7262507 | 0.91 | THRB (0.56) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Acrylic Acid SCHEMBL3925457 | 0.91 | HCAR2 (0.53) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Methacrylic Acid SCHEMBL9128151 | 0.90 | TSHR (0.51) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL42893 | 0.89 | HCAR2 (0.51) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL28121252 | 0.88 | THRB (0.48) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Methane SCHEMBL4468486 | 0.88 | HCAR2 (0.50) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| SCHEMBL40718 | 0.88 | THRB (0.67) | THRBHCAR2AKR1B10AKR1B1MAOB | |
| Methacrylic Acid SCHEMBL8131805 | 0.86 | HCAR2 (0.49) | THRBHCAR2AKR1B10AKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090160075-A1 | METHODS FOR FABRICATING CUSTOMIZED INTRAOCULAR LENSES | ALCON, INC, (CH) | 2009-06-25 | — | — | US | disclosed |