Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816350 | 0.89 | LMNA (0.57) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7595480 | 0.83 | RAB9A (0.46) | RAB9ANPC1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7566806 | 0.83 | LMNA (0.48) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7569442 | 0.83 | LMNA (0.48) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7575615 | 0.83 | RAB9A (0.46) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7785666 | 0.83 | RAB9A (0.47) | RAB9ANPC1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7565655 | 0.83 | LMNA (0.55) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7777694 | 0.83 | RAB9A (0.45) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL7593322 | 0.83 | RAB9A (0.45) | RAB9ANPC1LMNAKMT2AMEN1 | |
| SCHEMBL6816658 | 0.82 | RAB9A (0.60) | RAB9ANPC1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |