Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 5/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891553 | 0.81 | TRPA1 (0.56) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3513736 | 0.77 | TRPA1 (0.41) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15160874 | 0.75 | ALDH1A1 (0.57) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29029409 | 0.74 | TSHR (0.44) | ALDH1A1TRPA1RAB9ATSHR | |
| SCHEMBL27442791 | 0.74 | ALDH1A1 (0.53) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28015795 | 0.73 | SLC6A2 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9555833 | 0.71 | ALDH1A1 (0.65) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6530791 | 0.71 | TRPA1 (0.81) | ALDH1A1MEN1KMT2ASMN1; SMN2TRPA1 | |
| SCHEMBL28489101 | 0.70 | TOP1 (0.44) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14078677 | 0.69 | MIF (0.70) | MIFALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003050105-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CHEMINOVA A/S (DK) | 2003-06-19 | — | — | WO | disclosed |