Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578135 | 0.77 | CHRM1 (0.44) | ALDH1A1NPSR1LMNAADORA3AADAT | |
| SCHEMBL4706317 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAADORA3AADATHSD17B10 | |
| SCHEMBL18974998 | 0.72 | ALDH1A1 (0.47) | ALDH1A1NPSR1LMNAADORA3AADAT | |
| SCHEMBL14005648 | 0.71 | DRD4 (0.51) | LMNAAADATMEN1KMT2ATSHR | |
| SCHEMBL38661427 | 0.70 | ALDH1A1 (0.44) | ALDH1A1NPSR1LMNAADORA3HSD17B10 | |
| SCHEMBL4704022 | 0.70 | RIPK1 (0.46) | LMNAADORA3KMT2AGSK3BTSHR | |
| SCHEMBL1562250 | 0.70 | RIPK1 (0.46) | LMNAADORA3KMT2AGSK3BTSHR | |
| SCHEMBL1562248 | 0.70 | RIPK1 (0.46) | LMNAADORA3KMT2AGSK3BTSHR | |
| SCHEMBL4985948 | 0.69 | ALDH1A1 (0.41) | ALDH1A1NPSR1LMNAADORA3MEN1 | |
| Hydrochloric Acid SCHEMBL2233646 | 0.69 | RIPK1 (0.45) | LMNAADORA3KMT2AGSK3BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544978-B2 | Treating Alzheimer's disease both prophylactically and therapeutically | ATHENA NEUROSCIENCES, INC. | 2003-04-08 | — | — | US | disclosed |