SCHEMBL71624

SCHEMBL71624

C=C(C)C(=O)OCCN1C=NCC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28141626 0.80 KMT2A (0.32) ALDH1A1POLBHTT
Methacrylic Acid SCHEMBL71625 0.75
SCHEMBL4428120 0.74 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL235038 0.73 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL12860038 0.73 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8792090 0.73 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9281113 0.72 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16739318 0.71 THRB (0.45) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL38662511 0.71 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL68168 0.70 THRB (0.47) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790368-B2 Pearlescent pigments coated with mixed inorganic/organic layers and method for the production thereof ECKART GMBH (DE) 2017-10-17 US disclosed
CN-103509303-B With improved resistance to washing property and with the emulsion polymer of one or more silicon-containing compounds 塞拉尼斯销售德国有限公司 2017-07-18 CN disclosed
CN-106661136-A Process for emulsion polymerization of free-radically polymerizable, ethylenically unsaturated monomers 塞拉尼斯销售德国有限公司 2017-05-10 CN disclosed
US-20150183995-A1 PEARLESCENT PIGMENTS COATED WITH MIXED INORGANIC/ORGANIC LAYERS AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2015-07-02 US disclosed
US-9000068-B2 Metal effect pigments comprising a mixed inorganic/organic layer, method for the production of such metal effect pigments, and use thereof ECKART GMBH (DE) 2015-04-07 US disclosed
US-8980976-B2 Pearlescent pigments coated with mixed inorganic/organic layers and method for the production thereof ECKART GMBH (DE) 2015-03-17 US disclosed
US-8129021-B2 Effect pigments based on substrates formed from inorganic-organic mixed phases, production and use thereof ECKART GMBH (DE) 2012-03-06 US disclosed
US-20100298469-A1 EFFECT PIGMENTS BASED ON SUBSTRATES FORMED FROM INORGANIC-ORGANIC MIXED PHASES, PRODUCTION AND USE THEREOF ECKART GMBH (DE) 2010-11-25 US disclosed
US-20090252772-A1 PEARLESCENT PIGMENTS COATED WITH MIXED INORGANIC/ORGANIC LAYERS AND METHOD FOR THE PRODUCTION THEREOF ECKART GMBH (DE) 2009-10-08 US disclosed
US-20080249209-A1 Metal Effect Pigments Comprising a Mixed Inorganic/Organic Layer, Method for the Production of Such Metal Effect Pigments, and Use Thereof ECKART GMBH (DE) 2008-10-09 US disclosed