Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71624 | 0.74 | THRB (0.40) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9281113 | 0.70 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL150780 | 0.70 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2036447 | 0.69 | THRB (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL211511 | 0.69 | MGLL (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL4188784 | 0.69 | THRB (0.44) | THRBTSHRPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL38662511 | 0.69 | THRB (0.41) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL16739318 | 0.69 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL28189802 | 0.69 | KMT2A (0.43) | KMT2ANPSR1 | |
| SCHEMBL31556453 | 0.68 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091983-A1 | AMPHIPHILIC GRAFT POLYMERS | Sued-Chemie AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008046652-A1 | AMPHIPHILIC GRAFT POLYMERS | Süd-Chemie AG (DE) | 2008-04-24 | — | — | WO | disclosed |