Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485692 | 0.80 | CHRNA7 (0.74) | CHRNA7TDP1L3MBTL1CYP2A6CHRNB2 | |
| SCHEMBL724866 | 0.80 | CHRNA7 (0.74) | CHRNA7TDP1L3MBTL1CYP2A6CHRNB2 | |
| SCHEMBL16037351 | 0.80 | CHRNA7 (0.57) | CHRNA7TDP1L3MBTL1CYP2A6HRH1 | |
| SCHEMBL1477204 | 0.79 | — | — | |
| SCHEMBL15165321 | 0.77 | CHRNA7 (0.58) | CHRNA7TDP1L3MBTL1CYP2A6CHRNB2 | |
| SCHEMBL173147 | 0.77 | — | — | |
| SCHEMBL30672504 | 0.77 | — | — | |
| SCHEMBL2240266 | 0.77 | — | — | |
| SCHEMBL2843094 | 0.76 | CYP2A6 (0.76) | CHRNA7TDP1L3MBTL1CYP2A6HRH1 | |
| SCHEMBL29485675 | 0.76 | TDP1 (0.80) | CHRNA7TDP1L3MBTL1CYP2A6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998934-A1 | REMEDIES FOR INTRAMEDULLARY DISEASES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | claimed |
| US-6555529-B1 | Administering (4-methylthiophenylthio)methane-1,1-bisphosphonic acid for treatment of bone marrow disorders such as inflammatory disease, myeloma, anemia, and leukemia | TORAY INDUSTRIES, INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-0998934-A1 | REMEDIES FOR INTRAMEDULLARY DISEASES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5071482-A | Containing an antiflocculant additive | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |