Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27258122 | 1.00 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL524476 | 1.00 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL524284 | 1.00 | — | — | |
| Phosphoric Acid SCHEMBL28289818 | 1.00 | CA2 (0.46) | CA2SLC34A1KDM4EMMP2THRB | |
| Phosphoric Acid SCHEMBL6548178 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL2927432 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL28980286 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL29131461 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL232801 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL6461927 | 0.94 | CA2 (0.42) | CA2SLC34A1KDM4EMMP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028574-A1 | SURFACE ENGINEERED METAL SUBSTRATES AND RELATED METHODS | Novelis, Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| CN-114599815-A | Surface engineered metal substrates and related methods | 诺维尔里斯公司 | 2022-06-07 | — | — | CN | disclosed |
| WO-2021050876-A1 | SURFACE ENGINEERED METAL SUBSTRATES AND RELATED METHODS | NOVELIS INC. (US) | 2021-03-18 | — | — | WO | disclosed |
| JP-2003251273-A | METHOD OF COATING AUTOMOBILE CAR BODY | KANSAI PAINT CO LTD | 2003-09-09 | — | — | JP | disclosed |
| US-4806437-A | CHEMICAL CONVERSION COATING LAYER OF ZINC PHOSPHATE AND-OR CALCIUM ZINC PHOSPHATE | TOYODA GOSEI CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |