SCHEMBL716309

SCHEMBL716309

C=CCOc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
MAPT P10636 4/20 0.54
MEN1 O00255 1/20 0.54
PTPN7 P35236 1/20 0.54
KMT2A Q03164 1/20 0.54
PTPN12 Q05209 1/20 0.54
EGFR P00533 1/20 0.51
ERBB2 P04626 1/20 0.51
HSD17B10 Q99714 3/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
FFAR1 O14842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723595 0.84 GAA (0.52) ALDH1A1MAPTMEN1KMT2AEGFR
SCHEMBL8737479 0.84 NPC1 (0.49) ALDH1A1MAPTEGFRERBB2MAPK1
SCHEMBL22319825 0.82 MAPT (0.46) ALDH1A1MAPTMEN1KMT2AEGFR
SCHEMBL16371575 0.82 AOC3 (0.54) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL88417 0.82 AOC3 (0.54) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL11648906 0.81 ALDH1A1 (0.54) ALDH1A1MAPTMEN1PTPN7KMT2A
SCHEMBL29952681 0.81 ALDH1A1 (0.59) ALDH1A1MAPTMEN1PTPN7KMT2A
SCHEMBL3744653 0.80 CA12 (0.55) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL31591236 0.80 CA12 (0.55) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL3730541 0.80 AOC3 (0.52) ALDH1A1MAPTMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120235148-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 US disclosed
EP-2479791-A1 PHOTO-CROSSLINKABLE MATERIAL FOR ORGANIC THIN FILM TRANSISTOR INSULATING LAYER Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
CN-102484141-A Photo-crosslinking organic thin film transistor insulating layer material SUMITOMO CHEMICAL CO 2012-05-30 CN disclosed
US-20120053287-A1 RESIN COMPOSITION FOR INSULATING LAYER SUMITOMO CHEMICAL COMPANY, LTD (JP) 2012-03-01 US disclosed
CN-102282186-A Resin composition for insulating layer 2011-12-14 CN disclosed