SCHEMBL9723595

SCHEMBL9723595

C=CCOc1cccc(Nc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ALDH1A1 P00352 3/20 0.48
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
AR P10275 1/20 0.48
BCHE P06276 1/20 0.46
EGFR P00533 1/20 0.45
ERBB2 P04626 1/20 0.45
FFAR1 O14842 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
FGFR1 P11362 1/20 0.43
CYP3A4 P08684 2/20 0.42
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL716309 0.84 ALDH1A1 (0.54) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL3661946 0.81 GAA (0.53) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL2089601 0.81 MAPT (0.54) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL1520719 0.80 MEN1 (0.50) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL23121252 0.80 GAA (0.62) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL16371575 0.78 AOC3 (0.54) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL88417 0.78 AOC3 (0.54) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL7986906 0.77 MAPT (0.54) KDM4ENPC1RAB9AALDH1A1MAPT
SCHEMBL4981424 0.77 LTA4H (0.47) GAAKDM4ENPC1RAB9AALDH1A1
SCHEMBL6095961 0.76 CTSV (0.51) BCHECTSVCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112924-A Multilayer fabric, fiber or particle composite of improved heat resistance and high strength HERCULES INCORPORATED (US) 1992-05-12 US disclosed
US-5096766-A Prepregs HERCULES INCORPORATED (US) 1992-03-17 US disclosed
US-4946908-A DAMAGE TOLERANCE, SHEAR STRENGTH, THERMOCRACKING HERCULES INCORPORATED (US) 1990-08-07 US disclosed
EP-0363524-A1 Bismaleimide compositions containing high glass transition temperature and soluble reactive oligomers and composites prepared therefrom HERCULES INCORPORATED (US) 1990-04-18 EP disclosed