Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | USP2 | O75604 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938488 | 0.79 | CYP1B1 (0.44) | KMT2AMEN1MAPTTHRBPOLB | |
| 6-Hydroxy-1H-Phenalen-1-One SCHEMBL6229904 | 0.79 | MEN1 (0.47) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL4978813 | 0.78 | KEAP1 (0.50) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL28962252 | 0.76 | IDO1 (0.42) | KMT2AMEN1USP2MAPTTHRB | |
| 6-Methoxy-1H-Phenalen-1-One SCHEMBL8372712 | 0.75 | PRMT1 (0.53) | KMT2AMEN1USP2MAPTPOLB | |
| SCHEMBL27576058 | 0.73 | MAPT (0.41) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL26977395 | 0.71 | GUSB (0.39) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL236503 | 0.71 | CDC25B (0.46) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL30051046 | 0.71 | CDC25B (0.46) | KMT2AMEN1USP2MAPTTHRB | |
| SCHEMBL1310003 | 0.71 | CDC25B (0.46) | KMT2AMEN1USP2MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-5576424-A | ANALYZING METABOLIC ACTIVITY OF ENZYMES | MOLECULAR PROBES, INC. (US) | 1996-11-19 | — | — | US | disclosed |
| US-5362628-A | Analyzing | MOLECULAR PROBES, INC. (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0603266-A1 | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS | MOLECULAR PROBES, INC. (US) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993004192-A1 | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5154887-A | Useful in rapid and highly sensitive immunoassays | EASTMAN KODAK COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0231125-B1 | HYDROLYZABLE FLUORESCENT SUBSTRATES AND ANALYTICAL DETERMINATIONS USING SAME | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5055414-A | PHENALENIMINE FLUORESCENT DYES AND THEIR USE IN ANALYTICAL METHODS | EASTMAN KODAK COMPANY (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0353868-A2 | Phenalenimine fluorescent dyes and their use in analytical compositions, elements and methods | EASTMAN KODAK COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4812409-A | FOR HYDROLYTIC ENZYMES | EASTMAN KODAK COMPANY (US) | 1989-03-14 | — | — | US | disclosed |
| EP-0231125-A2 | Hydrolyzable fluorescent substrates and analytical determinations using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | KMT2A 3286/4885MEN1 606/4885USP2 3927/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | KMT2A 3286/4885MEN1 606/4885USP2 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.