Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167672 | 0.86 | P2RX4 (0.50) | P2RX4NOTUMKMT2AALDH1A1MEN1 | |
| SCHEMBL30877017 | 0.86 | KMT2A (0.50) | NOTUMKMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL27312108 | 0.86 | KMT2A (0.50) | NOTUMKMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL7162130 | 0.86 | L3MBTL1 (0.53) | P2RX4NOTUMKMT2AALDH1A1MEN1 | |
| SCHEMBL7171723 | 0.85 | TUBB1 (0.50) | P2RX4KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL7168990 | 0.84 | P2RX4 (0.50) | P2RX4NOTUMKMT2AALDH1A1MEN1 | |
| SCHEMBL600415 | 0.78 | NOTUM (0.61) | NOTUMKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL30109103 | 0.78 | NOTUM (0.61) | NOTUMKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27312100 | 0.78 | IDO1 (0.56) | NOTUMKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL9880603 | 0.77 | KMT2A (0.63) | P2RX4KMT2AALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540192-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | claimed |
| US-6566533-B1 | Reacting aza-heterocyclic compounds (indoles and carbazoles) with alkyl- or aryl-halides in the presence of carbon dioxide and alkali carbonate | WARNER-LAMBERT COMPANY LLC | 2003-05-20 | — | — | US | disclosed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | disclosed |