Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717982 | 0.94 | MAPT (0.47) | HSD11B1RARBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3474362 | 0.94 | MAPT (0.47) | HSD11B1RARBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7672033 | 0.75 | MKNK1 (0.38) | TSHRCA2CA1 | |
| SCHEMBL6393604 | 0.75 | SKP2 (0.34) | RAB9ASMN1; SMN2NPC1TSHRTP53 | |
| SCHEMBL10614683 | 0.75 | RAB9A (0.36) | RAB9ASMN1; SMN2NPC1TSHRALDH1A1 | |
| SCHEMBL8198894 | 0.75 | ESR1 (0.41) | RAB9ASMN1; SMN2NPC1TSHRTP53 | |
| SCHEMBL28829434 | 0.73 | RARB (0.67) | HSD11B1RARBNISCHRAB9ASMN1; SMN2 | |
| SCHEMBL5551587 | 0.73 | RARB (0.67) | HSD11B1RARBNISCHRAB9ASMN1; SMN2 | |
| SCHEMBL9718812 | 0.72 | HPGD (0.38) | NISCHRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL16429156 | 0.72 | RAB9A (0.49) | HSD11B1RARBNISCHRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019407-B1 | METALLO-PORPHYRINS | QINETIQ LTD (GB) | 2003-08-20 | — | — | EP | disclosed |