Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TST | Q16762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614683 | 0.86 | RAB9A (0.36) | CYP3A4KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL2316800 | 0.84 | GCGR (0.40) | ESR1CYP3A4ADRA2AADORA3TACR2 | |
| SCHEMBL2313952 | 0.84 | GCGR (0.40) | ESR1CYP3A4ADRA2AADORA3TACR2 | |
| SCHEMBL2314604 | 0.84 | RARB (0.51) | TP53ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2337738 | 0.84 | GCGR (0.40) | ESR1CYP3A4ADRA2AADORA3TACR2 | |
| SCHEMBL2310945 | 0.84 | RARB (0.51) | TP53ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL17681578 | 0.83 | CASP3 (0.42) | ALDH1A1MAPTNPC1RAB9ACCNB2 | |
| SCHEMBL17681582 | 0.83 | CASP3 (0.42) | ALDH1A1MAPTNPC1RAB9ACCNB2 | |
| SCHEMBL2319620 | 0.81 | MAPT (0.43) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1194296 | 0.81 | KCNH2 (0.35) | ESR1CYP3A4ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107480-A | 5-(HYDROXYLATEDPHENYL) PORPHYRIN DERIVATIVES WHICH MAY BE COVALENTLY BONDED TO SPECIFIED POLYMERS VIA THE HYDROXYLATED PHENYL GROUP; USE AS PHOTOSENSITIZERS FOR THE CATALYTIC FORMATION OF SINGLET OXYGEN | DLR, DEUTSCHE ZENTRUM FUR LUFT UND RAUMFAHRT E.V. (DE) | 2000-08-22 | — | — | US | disclosed |