Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460275 | 0.87 | CYP2C19 (0.43) | TSHRNFKB1CYP2C19ALDH1A1LMNA | |
| SCHEMBL561948 | 0.84 | FFAR4 (0.34) | TSHRNFKB1FFAR4FFAR1CYP2C19 | |
| SCHEMBL2052956 | 0.82 | FFAR4 (0.39) | TSHRNFKB1FFAR4FFAR1CYP2C19 | |
| SCHEMBL11809146 | 0.75 | FOLH1 (0.42) | TSHRNFKB1FFAR4FFAR1CYP2C19 | |
| SCHEMBL9513447 | 0.75 | FFAR4 (0.34) | TSHRNFKB1FFAR4FFAR1CYP2C19 | |
| Octanedioate SCHEMBL30741313 | 0.75 | TSHR (0.46) | TSHRNFKB1FFAR4FFAR1ALDH1A1 | |
| Sebacic Acid SCHEMBL28325940 | 0.75 | TSHR (0.46) | TSHRNFKB1FFAR4FFAR1ALDH1A1 | |
| Sebacic Acid SCHEMBL7179944 | 0.75 | TSHR (0.46) | TSHRNFKB1FFAR4FFAR1ALDH1A1 | |
| Sebacic Acid SCHEMBL480504 | 0.75 | TSHR (0.46) | TSHRNFKB1FFAR4FFAR1ALDH1A1 | |
| SCHEMBL17537055 | 0.74 | CA2 (0.42) | TSHRNFKB1FFAR4FFAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171613-B | Ultraviolet light absorbing ketones of 2- (2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2013-06-05 | — | — | CN | claimed |
| EP-3189099-B1 | HYDROXYBENZOPHENONE-BASED STABILIZERS AND POLYMERS END-CAPPED WITH THE SAME | SOLVAY SPECIALTY POLYMERS USA (US) | 2018-07-11 | — | — | EP | disclosed |
| CN-105602102-A | Low-density, high-strength and scratch-resistant modified polypropylene composite material and preparation method thereof | SHANGHAI PRET COMPOSITES CO | 2016-05-25 | — | — | CN | disclosed |
| CN-103524682-B | Reaction is extruded and is prepared the method for high melt strength, propylene from aggressiveness | ZHEJIANG UNIVERSITY (CN) | 2016-05-04 | — | — | CN | disclosed |
| US-8354529-B2 | Polyamine derivative and polyol derivative | BASF SE (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2511274-A2 | Polyamine derivative | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2484677-A1 | Polyamine derivative | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | MITA NARUYOSHI (JP) | 2012-03-01 | — | — | US | disclosed |
| US-8076478-B2 | Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance | BASF SE (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | CIBA CORPORATION | 2008-09-25 | — | — | US | disclosed |
| EP-1840127-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
| CN-1184117-A | Novel alpha-aminoacetophenone photoinitiators | CIBA SC HOLDING AG (CH) | 1998-06-10 | — | — | CN | disclosed |
| EP-0708138-A1 | Amine stabilized amorphous phosphite | GENERAL ELECTRIC COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | H1-0, H1-3, NPM1 | TSHR 1497/4885NFKB1 2408/4885FFAR4 3369/4885 |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | H1-0, H1-3, H1-2 | TSHR 1217/4885NFKB1 2263/4885FFAR4 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.