Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453278 | 0.82 | TSHR (0.43) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL11258656 | 0.82 | TSHR (0.37) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL17537055 | 0.80 | CA2 (0.42) | FOLH1TSHRNFKB1CYP2C19FFAR4 | |
| Sebacic Acid SCHEMBL28583209 | 0.79 | GPR84 (0.44) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL716438 | 0.75 | TSHR (0.39) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| Sebacic Acid SCHEMBL8958570 | 0.75 | TSHR (0.56) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL11769103 | 0.74 | FOLH1 (0.67) | FOLH1TSHRNFKB1FFAR4FFAR1 | |
| SCHEMBL1234699 | 0.74 | FOLH1 (0.67) | FOLH1TSHRNFKB1FFAR4FFAR1 | |
| SCHEMBL8639831 | 0.74 | FOLH1 (0.67) | FOLH1TSHRNFKB1FFAR4FFAR1 | |
| SCHEMBL30681842 | 0.74 | FOLH1 (0.67) | FOLH1TSHRNFKB1FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | claimed |
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | disclosed |